Patient Information
	•	Name: ANON
	•	Age: 73 years
	•	Exam Date: 02/04/2025
	•	Doctor: ANON
	•	Insurance: Private
	•	Facility: ANON
	•	Registration Number: ANON

PET/CT - Positron Emission Tomography Combined with Computed Tomography Using PSMA-18F

Technique:
	•	Radiotracer: PSMA-18F
	•	Dose: 8.0 mCi
	•	Uptake Time: 77 minutes

Protocol:
Tomographic images were acquired from the skull to the upper thigh using a dedicated PET/CT device after intravenous administration of the radiotracer. Diagnostic CT images of the same region were also obtained without intravenous injection of iodinated contrast. The study was supplemented with thoracic CT images taken during maximal inspiration. A venous diuretic (furosemide) was administered before imaging to reduce the interference of physiological urinary elimination in pelvic images.

Clinical Context

The patient, a 73-year-old male, was diagnosed with prostate adenocarcinoma and underwent a prostatectomy in 2024 (Gleason score 3+4 / pT2c, pN0). He has shown an increase in total serum PSA (0.35 ng/mL as of 01/28/2025). The PET-CT study was conducted for restaging.

Description

The fusion of molecular (PET) images with anatomical (CT) images does not reveal any areas with abnormally increased prostate-specific membrane antigen (PSMA) expression. Only the physiological distribution and elimination of the radiotracer were observed, consistent with the patient’s age.

CT Findings (Without Molecular Expression but Clinically Relevant)
	•	Lungs:
	•	Diffuse thickening of bronchial walls
	•	Small scattered non-calcified nodular opacities
	•	Atelectatic bands in lung bases
	•	Cardiovascular System:
	•	Atheromatous calcifications in the aorta, branches, and coronary arteries
	•	Liver:
	•	Residual calcified granulomas in segment IV
	•	Kidneys:
	•	Cystic formations in both kidneys (cortical and peripyelic)
	•	A small spontaneously dense lesion in the lower cortical region, suggestive of a dense cyst
	•	Colon:
	•	Multiple colonic diverticula, predominantly in the sigmoid colon, with no signs of inflammation
	•	Spine:
	•	Partial collapse of vertebral body D10
	•	Bilateral spondylolysis of L5 with a small associated anterolisthesis

Impression (Conclusion)
	•	No abnormal molecular PSMA expression detected using this method that would suggest malignancy.

Comments
	1.	The standardized uptake value (SUV) should be interpreted cautiously, as its diagnostic significance must be correlated with clinical and laboratory data. SUV values may vary depending on different equipment and study protocols.
	2.	The CT study performed during PET/CT follows a specific protocol for PET imaging and does not replace a dedicated diagnostic CT scan.


This report suggests that no recurrence or metastatic disease was detected based on PSMA expression. However, some incidental findings, such as lung nodules, renal cysts, and spinal changes, should be correlated with clinical history and monitored as needed.