Patient Information • Patient Name: ANON • Age: 76 years • Exam Date: 06/02/2025 • Physician: ANON • Insurance: Private • Facility: ANON PET/CT - Positron Emission Tomography Combined with Computed Tomography Using PSMA-18F Technique • Radiotracer: PSMA-18F • Dose: 8.4 mCi • Uptake Time: 83 minutes Protocol: • Tomographic images were acquired from the skull to the upper thigh using a dedicated PET/CT scanner after intravenous injection of the radiotracer. • Additional diagnostic CT images of the same region were taken without intravenous iodine contrast. • The study included high-inspiration thoracic CT images. • A venous diuretic (furosemide) was administered before imaging to minimize interference from urinary excretion in pelvic images. Clinical Context Patient, 75 years old, under investigation for prostate cancer. Findings Molecular Imaging (PET) and Anatomical Imaging (CT) Fusion Revealed: 1. Primary Prostate Lesion: • A solid, infiltrative mass affecting the prostate gland, centered at the right base, extending to the mid-third and involving the right seminal vesicle. • Size: 32 x 30 x 32 mm (width x thickness x depth) • Maximum SUV (Standardized Uptake Value): 10.8 2. Lymph Node Involvement: • Two affected lymph nodes in the right internal and external iliac chains: • First node: 9 x 8 mm, SUVmax 4.5 • Second node: 12 x 10 mm, SUVmax 15.1 3. No additional abnormal PET/CT findings, aside from normal age-related physiological distribution and elimination of the radiotracer. Additional CT Findings (Not Showing Molecular Uptake but Clinically Relevant): • Slight enlargement of the brain’s ventricular system (supratentorial ectasia). • Heterogeneous thyroid gland – Suggest correlation with ultrasound. • Surgical sternum closure (sternorraphy) visible. • Cardiac enlargement, mainly affecting the left chambers. • Subpleural bullae in the left upper lung lobe. • Small areas of atelectasis in the lingula and middle lung lobe. • Tiny, nonspecific nodular opacities (<3 mm) in the left lower lung lobe. • Hiatal hernia. • Gallstones (cholelithiasis). • Presence of a small accessory spleen. • Colonic diverticula without signs of acute inflammation. • Diffuse vascular calcifications. • No suspicious bone lesions detected. Impression/Conclusion • Primary malignant prostate cancer, locally advanced, with pelvic lymph node involvement on the right side. Comments & Considerations 1. SUV values (Standardized Uptake Values) should be interpreted cautiously and not used in isolation for diagnosis. They should be assessed alongside clinical and laboratory data. SUV values can vary between different scanners and study protocols. 2. The CT images obtained during PET/CT follow a specific PET protocol and are not a replacement for a dedicated diagnostic CT scan.